Fusidic acid
Fusidic acid is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Drug Products
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New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| fucidin | unapproved drug other | 2019-10-07 |
Indications
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Agency Specific
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ATC Codes
D: Dermatologicals
— D06: Antibiotics and chemotherapeutics for dermatological use
— D06A: Antibiotics for topical use
— D06AX: Other antibiotics for topical use in atc
— D06AX01: Fusidic acid
— D09: Medicated dressings
— D09A: Medicated dressings
— D09AA: Medicated dressings with antiinfectives
— D09AA02: Fusidic acid
J: Antiinfectives for systemic use
— J01: Antibacterials for systemic use
— J01X: Other antibacterials in atc
— J01XC: Steroid antibacterials
— J01XC01: Fusidic acid
S: Sensory organ drugs
— S01: Ophthalmologicals
— S01A: Antiinfective ophthalmologics
— S01AA: Antibiotics, ophthalmologic
— S01AA13: Fusidic acid
HCPCS
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Clinical
Clinical Trials
27 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Diabetic foot | D017719 | EFO_1001459 | — | 1 | — | 1 | 1 | — | 3 |
| Impetigo | D007169 | EFO_1000714 | L01 | — | — | 1 | 1 | 1 | 3 |
| Osteomyelitis | D010019 | EFO_0003102 | M86 | — | — | 1 | 1 | — | 2 |
| Diabetes mellitus | D003920 | EFO_0000400 | E08-E13 | — | — | — | 1 | — | 1 |
| Inflammation | D007249 | MP_0001845 | — | — | — | — | 1 | — | 1 |
| Blepharitis | D001762 | EFO_0009536 | H01.0 | — | — | — | 1 | — | 1 |
| Bacterial endocarditis | D004697 | EFO_1000830 | — | — | — | — | 1 | — | 1 |
| Endocarditis | D004696 | EFO_0000465 | I33 | — | — | — | 1 | — | 1 |
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Infections | D007239 | EFO_0000544 | — | — | 3 | 3 | — | 2 | 7 |
| Communicable diseases | D003141 | — | — | — | 2 | 2 | — | 2 | 5 |
| Infectious arthritis | D001170 | EFO_1001351 | M00 | — | 2 | 1 | — | 2 | 4 |
| Bacterial skin diseases | D017192 | — | — | — | 1 | 2 | — | — | 3 |
| Atopic dermatitis | D003876 | EFO_0000274 | L20 | — | — | 1 | — | 1 | 2 |
| Eczema | D004485 | — | L30.9 | — | — | 1 | — | 1 | 2 |
| Dermatitis | D003872 | — | L30.9 | — | — | 1 | — | 1 | 2 |
| Bacterial infections | D001424 | — | A49 | — | — | 2 | — | — | 2 |
| Non-small-cell lung carcinoma | D002289 | — | — | — | — | 1 | — | — | 1 |
| Lung neoplasms | D008175 | — | C34.90 | — | — | 1 | — | — | 1 |
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Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Skin diseases | D012871 | — | L00-L99 | — | 1 | — | — | — | 1 |
| Fibrosis | D005355 | — | — | — | 1 | — | — | — | 1 |
| Cystic fibrosis | D003550 | EFO_0000390 | E84 | — | 1 | — | — | — | 1 |
| Pulmonary fibrosis | D011658 | — | J84.10 | — | 1 | — | — | — | 1 |
Indications Phases 1
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Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Prosthesis-related infections | D016459 | EFO_1001406 | — | — | — | — | — | 2 | 2 |
| Staphylococcal infections | D013203 | — | A49.01 | — | — | — | — | 2 | 2 |
| Staphylococcus aureus | D013211 | NCBITaxon_1280 | — | — | — | — | — | 1 | 1 |
| Methicillin-resistant staphylococcus aureus | D055624 | — | — | — | — | — | — | 1 | 1 |
| Benign familial pemphigus | D016506 | — | Q82.8 | — | — | — | — | 1 | 1 |
| Psoriasis | D011565 | EFO_0000676 | L40 | — | — | — | — | 1 | 1 |
| Seborrheic keratosis | D017492 | EFO_0005584 | L82 | — | — | — | — | 1 | 1 |
| Keratosis | D007642 | — | — | — | — | — | — | 1 | 1 |
| Xanthomatosis | D014973 | — | — | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Fusidic acid |
| INN | fusidic acid |
| Description | Fusidic acid is a steroid antibiotic that is isolated from the fermentation broth of Fusidium coccineum. It has a role as a protein synthesis inhibitor, an EC 2.7.1.33 (pantothenate kinase) inhibitor and an Escherichia coli metabolite. It is a 3alpha-hydroxy steroid, an 11alpha-hydroxy steroid, a sterol ester, a steroid acid, an alpha,beta-unsaturated monocarboxylic acid and a steroid antibiotic. It is a conjugate acid of a fusidate. It derives from a hydride of a 5alpha-cholestane. |
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CC(=O)O[C@H]1C[C@@]2(C)[C@@H](C[C@@H](O)[C@H]3[C@@]4(C)CC[C@@H](O)[C@@H](C)[C@@H]4CC[C@@]32C)/C1=C(\CCC=C(C)C)C(=O)O |
Identifiers
| PDB | — |
| CAS-ID | 6990-06-3 |
| RxCUI | — |
| ChEMBL ID | CHEMBL374975 |
| ChEBI ID | 29013 |
| PubChem CID | 3000226 |
| DrugBank | DB02703 |
| UNII ID | 59XE10C19C (ChemIDplus, GSRS) |
Target
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Trends
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Safety
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Adverse Events
Top Adverse Reactions
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17,317 adverse events reported
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